Utilizing Virtual Reality to Improve the Ecological Validity of Clinical Neuropsychology

Zachariah Campbell, Konstantine K. Zakzanis, Diana Jovanovski, Steve Joordens, Richard Mraz, & Simon J. Graham - Nov. 2009

During the past century, our understanding of the relationship between brain and behavior has been elucidated in a monumental way. click here to read the article.


Quantitative evidence for distinct cognitive impairment in anorexia nervosa and bulimia nervosa

Konstantine K. Zakzanis*, Zachariah Campbell and Angelina Polsinelli - May 2009

The prevalence of eating disorders (ED) in North America is on the rise and it is estimated that 8% of females currently suffer from either anorexia nervosa (AN) or bulimia nervosa (BN) (American Psychiatric Association Work Group on Eating Disorders, 2000). click here to read the article


Age and dementia related differences in spatial navigation within an immersive virtual environment

Konstantine K. Zakzanis, Genevieve Quintin, Simon J. Graham, Richard Mraz - Apr. 2009

Neuropsychology has proceeded as a science by reducing complex behaviours into component cognitive domains. Domains of cognitive functioning identifi ed by neuropsychologists are numerous. click here to read the article


Visually navigating a virtual world with real-world
impairments: A study of visually and spatially guided
performance in individuals with mild cognitive impairments

William J. Tippett, Jang-Han Lee, Konstantine K. Zakzanis, Sandra E. Black, Richard Mraz, and Simon J. Graham - Aug. 2008

In recent years, use of virtual environments (VE) has increased in neuroscience research, stimulated in part by the explosive growth of computer technology and the video game industry. click here to read the article


Memory impairment in now abstinent MDMA users and continued users: A longitudinal follow-up

Konstantine K. Zakzanis, PhD; and Zachariah Campbell, MA - Nov. 2005

(±)3,4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) has neurotoxic effects on the serotonergic system in both animals and humans. The serotonergic system may play an important role in learning and memory systems. click here to read the article


A comparison of donepezil and galantamine in the treatment of cognitive symptoms of Alzheimer’s disease: a meta-analysis

Robin D. J. Harry and Konstantine K. Zakzanis - Feb. 2005

Alzheimer’s disease (AD), also known sometimes as dementia of the Alzheimer’s type, is the most prevalent cause of dementia in the aged population. click here to read the article


Memory impairment in abstinent MDMA (“Ecstasy”) users: A longitudinal investigation

Konstantine K. Zakzanis, PhD; and Donald A. Young, PhD - Dec. 2000

Several experimental studies indicate that ±3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”) damages brain serotonin (5-HT) in animals (including nonhuman primates) and possibly humans. click here to read the article


On the Nature and Pattern of Neurocognitive Function in Major Depressive Disorder

Konstantine K. Zakzanis, M.A., Larry Leach, Ph.D., and Edith Kaplan, Ph.D. - June 1998

Most clinical investigators accept the general notion that major depressive disorder is associated with neurocognitive abnormalities, but there arre many unresolved questions and controversies regarding their magnitude (severity), quality (pattern), and whether purported deficits are indicative of disturbed brain function. click here to read the article


Quantitative Evidence for Neuroanatomic and Neuropsychological Markers in Dementia of the Alzheimer’s Type

Konstantine K. Zakzanis - Feb. 1998

One of the most researched and established hypotheses regarding etiology in all of neuroscience posits involvement of the temporal-hippocampal formation as a core deficit in dementia of the Alzheimer’s type. click here to read the article